It is not yet 4/25/12, so I am assuming you mean 4/15/12. Vaccine reactions usually occur within 48 hours of the vaccine and the vast majority occur between 12 to 24 hours of the administration. The time frame here makes a vaccine reaction less likely. The symptoms you describe may be related to a vaccination reaction but may also be from an illness. Regardless, your dog needs medical attention. Contact your veterinarian for treatment and confirmation of the cause. Vaccine reactions can be treated successfully, especially if treatment is given quickly.